Tristan Rawling Selected Research

Glycine Plasma Membrane Transport Proteins

1/2022	Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl-D-Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice.
1/2021	The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity.
1/2020	Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2.
10/2019	Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics.
1/2019	Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.
1/2017	Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2.

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Tristan Rawling Research Topics

Disease

14	Neoplasms (Cancer) 01/2022 - 07/2012
11	Breast Neoplasms (Breast Cancer) 10/2021 - 08/2012
7	Chronic Pain 01/2022 - 01/2018
6	Pain (Aches) 01/2022 - 01/2017
2	Hyperalgesia 01/2022 - 01/2020
2	Kidney Neoplasms (Kidney Cancer) 01/2019 - 07/2012
2	Leukemia 06/2015 - 08/2013
2	Carcinoma (Carcinomatosis) 01/2015 - 08/2013
1	Neuralgia (Stump Neuralgia) 01/2022
1	Acute Pain 01/2022
1	Respiratory Insufficiency (Respiratory Failure) 01/2022
1	Drug-Related Side Effects and Adverse Reactions 04/2021
1	Obesity 01/2021
1	Hypersensitivity (Allergy) 01/2020
1	Necrosis 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 10/2019
1	Parkinson Disease (Parkinson's Disease) 01/2019
1	Iron Overload 01/2019
1	Liver Diseases (Liver Disease) 03/2018
1	Liver Cirrhosis (Hepatic Cirrhosis) 03/2018
1	Triple Negative Breast Neoplasms 12/2017
1	Skin Neoplasms (Skin Cancer) 06/2015
1	Carcinogenesis 08/2012

Drug/Important Bio-Agent (IBA)

9	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 09/2014
7	LipidsIBA 01/2022 - 04/2014
7	Sorafenib (BAY 43-9006)FDA Link 04/2021 - 07/2012
6	Glycine Plasma Membrane Transport ProteinsIBA 01/2022 - 01/2017
5	Palmitic Acid (Hexadecanoic Acid)IBA 01/2022 - 10/2017
5	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2022 - 01/2017
5	Antineoplastic Agents (Antineoplastics)IBA 04/2021 - 08/2012
5	Pharmaceutical PreparationsIBA 03/2019 - 07/2012
4	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2021 - 08/2012
3	Epoxy Compounds (Epoxides)IBA 10/2021 - 09/2014
3	AcidsIBA 10/2021 - 09/2014
3	Tyrosine Kinase InhibitorsIBA 04/2021 - 07/2012
3	Urea (Carbamide)FDA LinkGeneric 01/2020 - 01/2018
2	Analgesics (Analgesic Drugs)IBA 01/2021 - 10/2019
2	Amino Acids FDA Link 10/2020 - 01/2019
2	Phosphotransferases (Kinase)IBA 01/2019 - 08/2013
2	OxidesIBA 01/2019 - 08/2013
2	EnzymesIBA 03/2018 - 06/2015
2	Adenosine Triphosphate (ATP)IBA 04/2014 - 08/2013
1	4- benzyloxy- 3,5- dimethoxy- N- (1- (dimethylaminocyclopently)methyl)benzamideIBA 01/2022
1	Freund's AdjuvantIBA 01/2022
1	Opiate AlkaloidsIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	Paclitaxel (Taxol)FDA LinkGeneric 04/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Insulin (Novolin)FDA Link 01/2021
1	Glycine Receptors (Glycine Receptor)IBA 10/2020
1	Annexin A5IBA 01/2020
1	AmidesIBA 01/2020
1	caryophylleneIBA 01/2020
1	CarbonIBA 01/2020
1	7-aminoactinomycin DIBA 01/2020
1	p38 Mitogen-Activated Protein KinasesIBA 03/2019
1	CyclinsIBA 03/2019
1	quinone (benzoquinone)IBA 01/2019
1	Dopamine (Intropin)FDA LinkGeneric 01/2019
1	alpha-SynucleinIBA 01/2019
1	IronIBA 01/2019
1	Levodopa (L Dopa)FDA LinkGeneric 01/2019
1	QuinonesIBA 01/2019
1	Dihydrotachysterol (AT 10)IBA 10/2018
1	Cytochrome P-450 CYP3AIBA 03/2018
1	Imatinib Mesylate (Gleevec)FDA Link 03/2018
1	BilirubinIBA 03/2018
1	cytochrome P-450 CYP2C subfamilyIBA 03/2018
1	Serum AlbuminIBA 03/2018
1	Ion Channels (Ion Channel)IBA 01/2018
1	17,18-epoxy-5,8,11,14-eicosatetraenoic acidIBA 12/2017
1	CytochromesIBA 12/2017
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/2017
1	Biological ProductsIBA 11/2017
1	AlkaloidsIBA 11/2017
1	Cardiolipins (Cardiolipin)IBA 10/2017
1	EicosanoidsIBA 06/2015
1	Eicosapentaenoic AcidIBA 06/2015
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 06/2015
1	Phospholipids (Phosphatides)FDA LinkGeneric 06/2015
1	Membrane LipidsIBA 06/2015
1	Lipoxygenase (Lipoxygenase-1)IBA 06/2015
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 06/2015
1	CeramidesIBA 06/2015
1	Cyclin D1IBA 08/2013
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2013
1	Monounsaturated Fatty AcidsIBA 08/2012
1	ProstaglandinsIBA 08/2012
1	Arachidonic Acid (Vitamin F)IBA 08/2012
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 08/2012
1	Prostaglandins EIBA 08/2012
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 08/2012

Therapy/Procedure

6	Analgesia 01/2022 - 01/2017
5	Therapeutics 01/2022 - 01/2018
1	Denervation 01/2019
1	Oral Administration 10/2018